EGFR-TKI Resistant Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A molecular genetic abnormality indicating the presence of resistance in the epidermal growth factor receptor-tyrosine kinase inhibitor domain, due to secondary mutations of the EGFR gene.

**Synonyms:** - EGFR Mutation Resulting in Tyrosine Kinase Inhibitor Resistance - EGFR Tyrosine Kinase Inhibitor Resistant Mutation