E3 Ubiquitin-Protein Ligase CBL-C

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase CBL-C (474 aa, ~52 kDa) is encoded by the human CBLC gene. This protein is involved in ubiquitination of tyrosine kinases, which promotes kinase degradation and modulates signaling pathways.

**Synonyms:** - CBLC - EC 2.3.2.27 - EC 6.3.2.-, Formerly - RING Finger Protein 57 - SH3-Binding Protein CBL-3 - SH3-Binding Protein CBL-C - Signal Transduction Protein CBL-C