Dihydro-5-Azacytidine

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity. (NCI04)

**Synonyms:** - 1,3,5-triazin-2(1H)-one, 4-amino-3, 6-dihydro-1-beta-D-ribofuranosyl monohydrochloride - 5,6-DIHYDRO-5-AZACYTIDINE - 5,6-Dihydro-5-azacytidine hydrochloride - 5,6-dihydro-5-azacytidine HCl - 5,6-dihydro-5-azacytidine hydrochloride - DHAC - DHAC