Acodazole

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity. (NCI04)

**Synonyms:** - 1H-imidazo[4,5-f]quinoline, acetamide deriv - ACODAZOLE - acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]-