PAX7/FOXO1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene (~2.5 kb) that results from a chromosomal translocation t(1;13)(p36;q14) which fuses intron 7 of the PAX7 gene with intron 1 of the FOXO1 gene. This rearrangement is associated with alveolar rhabdomyosarcoma and rare cases of embryonal rhabdomyosarcoma.

**Synonyms:** - PAX7-FKHR Fusion Gene - PAX7-FOXO1 Fusion Gene - PAX7-FOXO1 Gene Fusion - PAX7/FKHR Fusion Gene - PAX7::FOXO1 Fusion Gene