Actinomycin C3

**Semantic type:** Amino Acid, Peptide, or Protein|Antibiotic|Pharmacologic Substance

**Definition:** A natural analogue of actinomycin, a chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin C3 inhibits DNA replication as well as RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II.

**Synonyms:** - 2104-L-I - ACTINOMYCIN C3 - AY 3 - Actinomycin AY1 - Actinomycin I3 - Actinomycin VII - Aurathin-A3