D048069Level 6

Tumor Necrosis Factors

**Definition:** A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.

**Tree numbers:** - D12.644.276.374.750 - D12.776.467.374.750 - D23.529.374.750

**Synonyms:** - TNF Receptor Ligands

GET/api/v1/systems/mesh/nodes/D048069

Official DownloadPublic Domain (US Government)Source

Hierarchy Explorer

Hierarchy ExplorerChevron to expand - click title to open

D000074049Cytokine TWEAK

D053245RANK Ligand

D053300Tumor Necrosis Factor Ligand Superfamily Member 13

D053308Lymphotoxin-beta

D053326Tumor Necrosis Factor Ligand Superfamily Member 14

D053361Lymphotoxin alpha1, beta2 Heterotrimer

D053380Tumor Necrosis Factor Ligand Superfamily Member 15

Cross-system equivalences0

No cross-system equivalences mapped for this node.

Report a data issue