Core Binding Factor Alpha 1 Subunit

**Definition:** A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.

**Tree numbers:** - D12.776.930.155.200.100

**Synonyms:** - AML3 Transcription Factor - CBFA-1 Protein - CBFA1 Protein - CBFalpha Runt Domain Transcription Factor 1 - CBFalpha1 Protein - Acute Myeloid Leukemia 3 Protein - PEBP2alphaA Protein - Runx2 Protein - SEF1 Protein - SL3-3 Enhancer Factor 1 - Osf2 Transcription Factor