Pentamethylmelamine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A principal metabolite of hexamethylmelamine with antineoplastic activity. Pentamethylmelamine alkylates DNA and other macromolecules and forms DNA intrastrand and DNA-protein crosslinks, thereby preventing DNA replication. (NCI04)

**Synonyms:** - 1,3,5-Triazine-2,4,6-triamine, N,N,N',N', N''-pentamethyl-, monohydrochloride (9CI) - 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N''-pentamethyl-, monohydrochloride (9CI) - Melamine - Melamine, N2,N2,N4,N4,N6-pentamethyl-, monohydrochloride - N,N,N',N',N''-pentamethyl-1,3,5-triazine - PENTAMETHYLMELAMINE - PMM - Pentamethylmelamine MonoHCl - Pentamethylmelamine Monohydrochloride - Pentamethylmelamine monoHCl - Pentamethylmelamine monohydrochloride - melamine, N2,N2,N4,N4,N6-pentamethyl-, monohydrochloride