Antineoplastic Alkylating Agent

**Semantic type:** Chemical Viewed Functionally

**Definition:** An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth.

**Synonyms:** - Chemotherapy Alkylating Agents - Chemotherapy Alkylators