Phenesterin

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A steroidal nitrogen mustard with antineoplastic and mutagenic activities. After attachment to cell-surface steroid receptors and uptake, phenesterin enters the nucleus where it alkylates macromolecules, resulting in decreased cell proliferation. (NCI04)

**Synonyms:** - (3-beta)-cholest-5-en-3-ol 4-(bis(2-chloroethyl)amino)benzeneacetate - (4-(bis(2-chloroethyl)amino)phenyl)acetic acid cholesteryl ester - (p-(bis(2-chloroethyl)amino)phenyl) acetate cholesterol - (p-(bis(2-chloroethyl)amino)phenyl)acetic acid cholesteryl ester - 5-Cholesten-3-beta-ol 3-(p-(bis(2-chloroethyl)amino)phenyl)acetate - Cholest-5-en-3-ol, (3.beta.)-, 4-[bis(2-chloroethyl)amino]benzeneacetate - Cholest-5-en-3beta-ol 4-(bis(2-chloroethyl)amino)benzeneacetate - Cholesteryl p-bis(2-chloroethyl)aminophenylacetate - Fenesterin - Fenesterin - Fenestrin - Fenestrin - NCI-C01558 - NCI-C01558 - PHENESTERINE - Phenesterine - Phenesterine - p-bis(2-chloroethyl)amino phenylacetate cholesterol