HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

**Semantic type:** Neoplastic Process

**Definition:** A large B-cell lymphoma characterized by the presence of a diffuse proliferation of large, atypical HHV8-positive neoplastic lymphocytes. It usually arises in association with HHV8-positive multicentric Castleman disease.

**Synonyms:** - HHV8-Positive DLBCL, NOS - HHV8-Positive Diffuse Large B-Cell Lymphoma, NOS - Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified - KSHV/HHV8-Positive Diffuse Large B-Cell Lymphoma