Tyrosine-Protein Phosphatase Non-Receptor Type 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Tyrosine-protein phosphatase non-receptor type 1 (435 aa, ~50 kDa) is encoded by the human PTPN1 gene. This protein plays a role in endocytosis, the unfolded protein response, signaling and protein dephosphorylation.

**Synonyms:** - EC 3.1.3.48 - PTP-1B - PTPN1 - Protein Tyrosine Phosphatase, Non-Receptor Type 1 - Protein-Tyrosine Phosphatase 1B