Tyrosine-Protein Phosphatase Non-Receptor Type 22

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Tyrosine-protein phosphatase non-receptor type 22 (807 aa, ~92 kDa) is encoded by the human PTPN22 gene. This protein is involved in both protein dephosphorylation and modulation of T-cell receptor signaling.

**Synonyms:** - EC 3.1.3.48 - Hematopoietic Cell Protein-Tyrosine Phosphatase 70Z-PEP - LyP - Lymphoid Phosphatase - PEP - PEST-Domain Phosphatase - PTPN22 - Protein Tyrosine Phosphatase, Non-Receptor Type 22