Clonal T-Cell Receptor Gene Rearrangement

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** Rearrangements involving DNA recombinase and T-cell receptor family genes that result in the expression of antigen-specific T-cell receptor proteins. This process occurs during the differentiation of T-lymphocytes, such that individual T-cell progenitors, and their descendents, express identical forms of the T-cell receptor complex.

**Synonyms:** - Clonal TCR Gene Rearrangement - Monoclonal T-Cell Receptor Gene Rearrangement