Dacarbazine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04)

**Synonyms:** - 1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)- - 4-(Dimethyltriazeno)imidazole-5-carboxamide - 5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide - 5-(3-3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide - 5-(Dimethyltriazeno)imidazole-4-carboxamide - 5-(dimethyltriazeno)imidazole-4-carboxamide - Asercit - Biocarbazine - DACARBAZINE - DIC - DTIC - DTIC - DTIC-Dome - DTIC-Dome - DTIC-Dome - Dacarbazina - Dacarbazina Almirall - Dacarbazine - DTIC - Dacatic - Dakarbazin - Deticene - Deticene - Detimedac - Dimethyl (triazeno) imidazolecarboxamide - Dimethyl Triazeno Imidazol Carboxamide - Dimethyl Triazeno Imidazole Carboxamide - Dimethyl-triazeno-imidazole-carboximide - Fauldetic - Imidazole Carboxamide - Imidazole Carboxamide Dimethyltriazeno - Imidazole carboxamide - WR-139007 - dacarbazine - dimethyl-triazeno-imidazole carboxamide