Dianhydrogalactitol

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. (NCI04)

**Synonyms:** - 1,2,5,6 dianhydrogalactitol - 1,2:5, 6-Dianhydrogalactitol - 1,2:5, 6-diepoxydulcitol - 1,2:5,6 dianhydrogalactitol - 1,2:5,6-Dianhydrodulcitol - 1,2:5,6-Diepoxydulcitol - 1,2:5,6-dianhydrodulcitol - Bi-functional Alkylating Agent VAL-083 - Bi-functional Alkylating Agent VAL-083 - DAG - DIANHYDROGALACTITOL - Dianhydrodulcitol - Dulcitol diepoxide - Galactitol - Galactitol, 1,2:5,6-dianhydro- (8CI 9CI) - VAL-083 - VAL083 - dianhydrodulcitol - diepoxydulcitol - diepoxygalactitol - dulcitol diepoxide - galactitol, 1,2:5,6-dianhydro- (8CI 9CI)