Azetepa

**Semantic type:** Pharmacologic Substance

**Definition:** An azirine-based thiotepa derivative with alkylating activity. Azetepa is able to alkylate and crosslink DNA, causing DNA damages and eventually an inhibition of cellular proliferation.

**Synonyms:** - AZETEPA - Azatepa - CL 25477 - Phosphinic Amide, P,P-bis(1-aziridinyl)-N-ethyl-N-1,3,4-thiadiazol-2-yl-