Tauromustine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A water-soluble taurine-based nitrosourea with potential antineoplastic activity. Tauromustine alkylates DNA and causes DNA cross links independent of cell cycle, thereby resulting in disruption of DNA function and induction of apoptosis.

**Synonyms:** - 1-(2-Chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea - LS-2667 - TAUROMUSTINE - TCNU