Aclacinomycin Antitumor Antibiotic

**Semantic type:** Chemical Viewed Functionally

**Definition:** An oligosaccharide anthracycline antibiotic isolated from strains of the bacterium Streptomyces galilaeus with potential antineoplastic activity. These agents display potent antitumor properties due to their ability to intercalate into DNA and interfere with the function of both the topoisomerase I and II enzymes, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.

**Synonyms:** - Aclacinomycins - aAclacinomycin