Poly (ADP-Ribose) Polymerase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits Poly (ADP-Ribose) polymerase, an enzyme involved in detecting DNA single strand breaks and the initiation of DNA repair. Inhibition of Poly (ADP-Ribose) polymerase has direct cytotoxic effects by inhibiting DNA repair and causing cell death.

**Synonyms:** - PARP Inhibitor - PARP Inhibitor - PARP inhibitor - PARP inhibitor - Poly(ADP-Ribose) Polymerase Inhibitor - poly (ADP-ribose) polymerase inhibitor