Histone Deacetylase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation.

**Synonyms:** - HDAC Agent - HDAC inhibitor - histone deacetylase inhibitor